Neuroimmune modulation of pain and regenerative pain medicine

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منابع مشابه

pain and modulation processes

pain is one of the most important and sometimes difficult problems, that patients and physicians are encountered. it may be clinically acute or chronic, acute pain has usually definite cause and favourable response to treatment. on the other hand there are difficulties in diagnosis and management of chronic pain. peripheral and cranial nerves convey pain impulses toward central nervous system, ...

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Lifetime Modulation of the Pain System via Neuroimmune and Neuroendocrine Interactions

Chronic pain is a debilitating condition that still is challenging both clinicians and researchers. Despite intense research, it is still not clear why some individuals develop chronic pain while others do not or how to heal this disease. In this review, we argue for a multisystem approach to understand chronic pain. Pain is not only to be viewed simply as a result of aberrant neuronal activity...

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Personalized Pain Medicine: The Clinical Value of Psychophysical Assessment of Pain Modulation Profile

Experimental pain stimuli can be used to simulate patients' pain experience. We review recent developments in psychophysical pain testing, focusing on the application of the dynamic tests-conditioned pain modulation (CPM) and temporal summation (TS). Typically, patients with clinical pain of various types express either less efficient CPM or enhanced TS, or both. These tests can be used in pred...

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Neuroimmune Activation and Chronic Pain, AANA Journal, February 2011

AANA Journal ß February 2011 ß Vol. 79, No. 1 31 Chronic pain is an extremely debilitating disease syndrome for which current treatment modalities are largely ineffective. This article presents the recently proposed contributions of neuroimmune activation to the maintenance of chronic pain. The theory of neuroimmune activation postulates a pathway that links peripheral neuronal injury/inflammat...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 2020

ISSN: 0021-9738,1558-8238

DOI: 10.1172/jci134439